The health ministry in Gaza says the total number of Palestinians killed in Israeli attacks since October 7 is now 17,177, with more than 46,000 others wounded.
In the past 24 hours, 350 Palestinians have been killed, the ministry added.
Israel declared war on Hamas after the group’s October 7 attacks that killed 1,200 people, mostly civilians, according to Israeli authorities, and saw around 240 hostages taken.
Israel has vowed to destroy Hamas and free 138 hostages still held after scores were freed during a short-lived truce.
Several Hamas commanders were killed in an air strike near the Indonesia Hospital, the Israeli military said early Wednesday on X.
Sources in Hamas and Islamic Jihad, another Palestinian group, told AFP their fighters were battling Israeli troops early Wednesday in a bid to prevent them from breaking into Khan Yunis and surrounding areas.
Related: Gaza bombing can stop if Pakistan warns Israel: Hamas
According to the Hamas-run government media office, dozens of people were killed and injured in heavy strikes on areas east of Khan Yunis.
Meanwhile, areas in the central and northern Gaza Strip were still coming under bombardment, according to Hamas.
The Hamas-run health ministry said air strikes on the Nuseirat refugee camp in central Gaza killed six people and injured 14 others.
Yesterday, senior Political Leader of Hamas, Ismail Haniyeh suggested that if Israel faced resistance from Pakistan, the perpetration of cruelty could cease.
Praising Pakistan as a brave nation, he suggested that if Israel faced resistance from Pakistan, the perpetration of cruelty could cease. Expressing hope in Pakistan’s support, he referred to the country as a land of Mujahideen.
‘Nowhere is safe’
Israel had previously told civilians in the north of the densely populated Gaza Strip to seek shelter in the south of the territory, with many fleeing to Khan Yunis believing it would be safer.
As the war expands, Israel has told people to move even further south, sparking “panic, fear and anxiety”, according to Philippe Lazzarini, head of the UN agency for Palestinian refugees, UNRWA.
People were being pushed into an area that is less than one-third of the Gaza Strip, with roads to the south clogged, he said.
International aid groups have condemned the succession of orders to flee from one area to another, saying that civilians were running out of options.
“Nowhere is safe in Gaza,” said United Nations humanitarian chief Martin Griffiths.
“Not hospital, not shelters, not refugee camps. No one is safe.”
Following demands to create areas where civilians could shelter, Israel’s army published a map it said was intended to enable Gazans to “evacuate from specific places for their safety if required”.
But the UN criticised the map on Tuesday, saying it was impossible to create safe zones for civilians to flee to inside Gaza.
“The so-called safe zones… are not scientific, they are not rational, they are not possible, and I think the authorities are aware of this,” said James Elder, spokesman for the UN children’s agency UNICEF.
The violence in Gaza “now ranks amongst the worst assaults on any civilian population in our time and age”, according to the Norwegian Refugee Council, which also warned of the dire public health consequences of the approaching winter.
Their belongings piled onto donkey carts, battered vehicles and camels, Gazans headed south to try to escape the expanding Israeli offensive.
An estimated 1.9 million people are displaced in Gaza — roughly three-quarters of the population, according to UN figures.
In northern Gaza, the Israeli military said it had encircled the Jabalia refugee camp and also raided a Hamas Internal Security Forces command and control centre.
It said the number of Israeli soldiers killed since the war began had risen to 82.
According to the Hamas-run health ministry in Gaza, several people were killed and injured in Israeli strikes on Jabalia.
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